Introduction: This Is America

Introduction to B This is Watson

In 2007, IBM Research took on the grand challenge of building a computer system that could compete with champions at the game of Jeopardy!i. In 2011, the open-domain question-answering (QA) system, dubbed Watson, beat the two highest ranked players in a nationally televised two-game Jeopardy! match. This paper provides a brief history of the events and ideas that positioned our team to take on ...

Governing America: An Introduction

in the spring of 1995, i attended a session at the organization of American Historians conference at the Washington Hilton, which focused on the state of political history. When i walked toward the conference room i expected to find a small crowd, and one with little hope for the future. At the time, the political history field seemed bleak. senior practitioners, who, for at least two decades, ...

Editor’s Introduction to This Issue

With the recent development of high-throughput DNA microarray and next-generation sequencing techniques for detecting various genomic variants, genome-wide association studies (GWASs) have become a popular strategy to discover genetic factors affecting common complex diseases. Many GWASs have successfully identified genetic risk factors associated with common diseases and have achieved substant...

Editor's Introduction to This Issue

Next generation sequencing (NGS) has been facilitating the discovery and functional validation of causal variants in diverse rare diseases. However, for most of the 7,000 rare diseases, pathogenic mechanisms are still unknown. In this issue, Dr. Murim Choi's group (Seoul National University, Korea) comprehensively reviewed ultra-rare diseases and genomics-driven precision medicine. They present...

Focus on: Urban America Introduction